S4 (ANDARINE/ GTX-007)

S4 is a SARM with very similar properties to oxandrolone and winstrol, but its advantage is that it can inhibit lipoprotein lipase – an enzyme that causes fat accumulation. Additionally, S4 also maintains and even increases muscle mass in a high-calorie diet. Improves the “aesthetic” appearance of the muscle with little or no water retention. There are reports that even in people with muscle atrophy, SR allowed complete recovery of muscle mass without any training at a dose of 3 mg/kg per day. The effects appear 1 to 2 weeks after starting.

ACTION

S4 is a complete agonist of the androgen receptor in muscle tissue and a partial agonist in the prostate gland. S4 binds to androgen receptors in muscles and bones by improving protein synthesis, which in turn helps build more muscle mass and strengthen joints and bones. There are many cases where exercisers gain muscle mass while being in a calorie deficit! S4 (Andarine) can also reduce the level of lipoprotein lipase (an enzyme that hydrolyzes triglycerides in lipoproteins and is a key enzyme in the metabolism of fatty acids and lipoproteins in muscles – this leads to more difficult accumulation of subcutaneous fat. It also improves the aesthetic appearance of muscles, reduces water retention, makes the silhouette perfectly sculpted.

ADVANTAGES

• does not increase liver enzymes, which eliminates the risk of hepatotoxicity allows you to obtain lean muscle mass during the mass building period
• Does not adversely affect the lipid profile
• Does not aromatize
• protects muscles during reduction
• supports during reduction (fat burning) without a catabolic effect on muscles
• S4 can be combined with almost anything
• Favorable safety profile

DOSAGE

The best effects are achieved with doses between 25-50 mg/day. The daily dose should be divided into smaller daily doses due to the short half-life – optimally 3-4 times a day. The maximum daily dose is 100 mg.
It is suggested to be taken for at least 6-8 weeks minimum. At the lowest dose (e.g. 25 mg/day), the cycle can be extended to several months.

SIDE EFFECTS

• deterioration of night vision in some people
• Temporary mood depression in some people
• No human studies
• With high doses or long LGD cycles, it is possible to partially or completely block the HPTA axis and reduce testosterone secretion.

Remember to perform detailed blood tests and an assessment of your hormonal profile before use. To assess the initial condition of the pituitary gland and testicles (to know what values ​​should be returned to), the following tests should be performed:

• Free and total testosterone
• FSH
• LH
• Estardiol
• Prolactin
• SHBG
And other tests assessing the metabolic state and health of the body.

ATTENTION

In cycles with a dose of 50 mg and more over 8 weeks, it is recommended to include testosterone, because the agent does not aromatize and may cause low estradiol concentrations, manifested by, among others: low mood, libido or joint pain. When SARMs are added to testosterone, there are no such side effects.